1/15/2024 0 Comments Mog meaning of word1, 2, 4 While some long-term deficit was accumulated from the presenting attack (similar to prior reports), 1 additional attack-related EDSS score worsening in most patients suggests that attack prevention may be associated with lower long-term disability in relapsing MOGAD. Our finding of just 7% having an EDSS score of 6 or greater and 7% unilaterally blind or worse after a median of 14 years of follow-up is similar to outcomes in previous studies with shorter follow-up. We found that most patients with MOGAD had a favorable long-term outcome without secondary progression despite frequent relapses, differing from that reported with multiple sclerosis (MS) and aquaporin-4–IgG neuromyelitis optica spectrum disorders (NMOSDs). Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography. ![]() EDSS indicates Expanded Disability Status Scale NMO, neuromyelitis optica ON, optic neuritis TM, transverse myelitis VFS, visual functional system. Triple combinations were also used: steroids, rituximab, and IVIg, 2 steroids, rituximab, and oral immunosuppressant, 1 (7%). Of 14 patients who received combination treatment, the combinations included steroids and oral immunosuppressant, 13 steroids and rituximab, 5 steroids and IVIg, 4 rituximab and oral immunosuppressant, 1 and steroids and plasma exchange, 1. Twenty-three patients received 1 or more maintenance attack-prevention treatments, including MS medications excluding rituximab/ocrelizumab (n = 6) IVIg (n = 3) oral/intermittent IV steroids (n = 5) rituximab (n = 1) oral immunosuppressants (n = 6) or a combination (n = 14). Oral immunosuppressants included azathioprine, cyclophosphamide, methotrexate, or mycophenolate mofetil. Maintenance treatments with multiple sclerosis (MS) medications included any current or prior approved MS medications except rituximab and ocrelizumab. ![]() Short-term treatments were undertaken within 6 weeks and included 1 or more of corticosteroids (oral/intravenous ), intravenous immunoglobulin (IVIg), or plasma exchange.
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